Slow Aging | Healthy living, healthy aging

Elements of aging – Oxidative stress

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When metal parts age,  like the hinge on your door or nails in the fence, they become rusty. This chemical change alters the properties of metal. Instead of being sturdy and smooth, rusted metal is weakened, fragile and flaky. Ultimately, rust means that these objects don’t work as they should, the door creaks and the fence pails fall down with every puff of wind. This slow decline in structure and function is common to the aging process, as is its chemistry. Like the nails in the fence, we are also constantly exposed to oxygen.

Oxygen is the essence of the air we breathe. It is vital for the creation of energy. But this dependence comes at a cost. During metabolism a small proportion of oxygen is converted into toxic products, collectively known as Reactive Oxygen Species (ROS or free radicals). When attacked by free radicals, proteins, DNA and lipids don’t work as they should, and as with rusty metal, function declines. As we get older and our systems for metabolizing oxygen become less efficient, our production of free radicals increases. If the production of free radicals outstrips our (antioxidant) defense mechanisms, a state of oxidative stress is said to exist. Oxidative stress is one of the most important elements of the aging process. There is a lot we can do to bolter our antioxidant defenses, as well as erode them prematurely. Unequivocally, diets naturally high in antioxidants can improve health and prolong life and have done so for centuries.

Options for increasing your intake of antioxidants

Last Reviewed 03/Mar/2014

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Dr Merlin Thomas

Professor Merlin Thomas is Professor of Medicine at Melbourne’s Monash University, based in the Department of Diabetes. He is both a physician and a scientist. Merlin has a broader interest in all aspects of preventive medicine and ageing. He has published over 270 articles in many of the worlds’ leading medical journals

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